Delegated Regulation (EU) 2025/1222 of 2 April 2025 was published in the Official Journal of the European Union on 20 June 2025. This is the 23rd ATP (Adaptation to Technical and Scientific Progress) of the European CLP Regulation (Classification, Labelling and Packaging of Substances). It concerns a total of eight substances that may be used in cosmetics, including three with a classification as CMR, which ultimately threatens their use in cosmetic products. This Regulation shall apply from 1st February 2027.
The key points of Regulation (EU) 2025/1222
• This Regulation is based on the opinions formulated by the Risk Assessment Committee (RAC) of the European Chemicals Agency (ECHA) between 16 March 2023 and 14 September 2023 on the proposals for harmonised classification and labelling of certain substances.
• It involves a total of eight substances that may be used in cosmetic products (listed in CosIng, not present in Annex II of the Cosmetics Regulation, which lists prohibited ingredients).
• Three of these are classified as CMRs (Ozone, Nitrous Oxide, and Tetrahydrofurfuryl Methacrylate), which, in accordance with Article 15 of Regulation 1223/2009, paves the way for a possible ban on their use in cosmetics, unless exempted following an opinion from the SCCS. None of the three is currently subject to evaluation process by the Scientific Committee.
• This Regulation will apply from 1st February 2027.
“Cosmetic” ingredients added to Annex VI of CLP
Ozone
Identification
Index No
• 008-004-00-4
Chemical name
• ozone
CE No
• 233-069-2
CAS No
• 10028-15-6
Classification
Hazard class and …
