On 7 February 2025, the HSE (Health and Safety Executive), the Agency responsible for the CLP Regulation in Great Britain, published its Opinions on the harmonised classification and labelling of three ingredients for cosmetic use in the GB MCL (Mandatory Classification and Labelling), the equivalent of Annex VI of the European CLP Regulation.
Silver
For silver (CAS No.7440-22-4, EC No.231-131-3, INCI: Silver), the HSE proposes the following classifications.
Silver massive (particle diameter ≥ 1 mm)
• Repr. 2, H361f - Suspected of damaging fertility
• STOT RE 2, H373 - May cause damage to organs through prolonged or repeated exposure
Silver powder (particle diameter > 100 nm < 1 mm)
• Repr. 2 - H361f - Suspected of damaging fertility
• STOT RE 2, H373 - May cause damage to organs through prolonged or repeated exposure
• Aquatic Acute 1, H400 - Very toxic to aquatic life (M-Factor = 10)
• Aquatic Chronic 1, H410 - Very toxic to aquatic life with long lasting effects (M-Factor = 10)
Silver nano (particle diameter > 1 nm ≤ 100 nm)
• Repr. 2 - H361f - Suspected of damaging fertility
• STOT RE 2, H373 - May cause damage to organs through prolonged or repeated exposure
• Aquatic Acute 1, H400 - Very toxic to aquatic life (M-Factor = 1000)
• Aquatic Chronic 1, H410 - Very toxic to aquatic life with long lasting effects (M-Factor = 1000)
This Opinion is aligned with the provisions of Regulation (EU) 2024/2564 (22nd …
