On December 12, 2025, the International Fragrance Association (IFRA) launched a consultation on the 52nd Amendment to its Standards. This date also marks the start of the period for the new provisions to come into force. The consultation is open until June 12, 2026.
The consultation covers three aspects:
• all 69 Standards affected by changes (new and revised),
• the update of the Guidelines for the use of Standards,
• a detailed appendix compiling contributions from other sources, including information on presence in natural ingredients.
The New Standards
51 new restriction Standards are included in this 52nd Amendment.
40 new restriction Standards to address potential dermal sensitization effects, with additional evaluation of systemic toxicity endpoints
• Acetyl cedrene (CAS: 32388-55-9 / 68039-35-0; INCI: Acetylcedrene)
• p-Anisyl acetate (CAS: 104-21-2 / 1331-83-5; INCI: p-Anisyl Acetate)
• Butyl 2-methylbutyrate (CAS: 15706-73-7; INCI: -)
• Butyl trimethyl dioxane (CAS: 54546-26-8; INCI: Valeraldehyde Hexyleneglycol Acetal)
• Cuminylacetaldehyde (CAS: 7775-00-0; INCI: 3-p-Cumenyl Propionaldehyde)
• Dihydro farnesal (CAS: 194934-66-2 / 32480-08-3 / 51513-58-7 / 172376-82-8; INCI: -)
• Dihydromyrcenyl acetate (CAS: 53767-93-4; INCI: Dihydromyrcenyl Acetate)
• 1-Ethoxy-4-(tert-pentyl)cyclohexane (CAS: 181258-87-7 / 181258-89-9 / 1372159-68-6; INCI: -)
• Ethyl cinnamate (CAS: 103-36-6 / 4192-77-2 / 4610-69-9; INCI: Ethyl Cinnamate)
• Ethyl linalyl acetate (CAS: 61931-80-4 / 1082679-69-3 / 2768000-97-9; INCI: Homolinalyl acetate)
• Geranyl and Neryl acetate (CAS: 105-87-3 / 141-12-8 / 16409-44-2); INCI: Geranyl Acetate / Neryl Acetate / Citryl Acetate)
• Geranyl and Neryl isovalerate (CAS: …
