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Thursday, October 1, 2026ECHA

Consultation on the CLH classification of Padimate O

Consultations CLH Padimate O

On September 28, 2026, the European Chemicals Agency (ECHA) opened a consultation on Spain’s proposal for harmonized classification and labeling (CLH) of several dimethylaminobenzoate derivatives, including the UV filter Padimate O, as Reprotoxic category 1B.

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This consultation concerns three substances, two of which are ingredients authorised for use in cosmetics:
• Ethyl 4-dimethylaminobenzoate (CAS No.10287-53-3; EC No.233-634-3; INCI: Ethyl dimethyl PABA; CosIng function: Light stabilizer) ;
• 2-ethylhexyl 4-(dimethylamino)benzoate (CAS No.21245-02-3; EC No.244-289-3; INN: Padimate O; INCI: Ethylhexyl Dimethyl PABA; CosIng functions: Light stabilizer, UV absorver, UV filter).

Ethyl dimethyl PABA is not currently regulated by European Cosmetics Regulation 1223/2009.
Ethylhexyl Dimethyl PABA, on the other hand, is listed in Annex VI/21 (Authorised UV filters), which limits its maximum concentration in finished products to 8%.
Neither is currently listed in Annex VI of the European CLP Regulation 1272/2008.

Spain proposes to classify the substance as follows.

Identification
Index number
• TBD
Chemical name
• ethyl 4-dimethylaminobenzoate ; 2-ethylhexyl 4-(dimethylamino)benzoate
EC number
• 233-634-3 ; 244-289-3
CAS number
• 10287-53-3 ; 21245-02-3
Classification
Hazard class and Category code(s)
• Repr. 1B
Hazard statement code(s)
• H360F - May damage fertility.
Labelling
Pictogram, Signal word code(s)
• GSH08
• Dgr (Danger)
Hazard statement code(s)
• H360F - May damage fertility.
Suppl. Hazard statement Code(s)
• /
Specific concentration …

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