On June 11, 2025, the European Chemicals Agency (ECHA) announced Sweden’s intention to propose the harmonized classification and labeling (CLH) of the preservative Silver Chloride, notably as a mutagenic and reprotoxic substance.
Silver chloride deposited on titanium dioxide (CAS No.7783-90-6, EC No.232-033-3, INCI: Silver Chloride) is an ingredient listed in Cosing, with the function: Preservative.
The substance is listed in Annex V/52 of European Cosmetics Regulation 1223/2009 which limits its maximum concentration to 0.004% (as AgCl), and bans it in products for children under 3 years of age, in oral products and in eye and lip products.
It is not currently listed in Annex VI of the European CLP Regulation 1272/2008.
Sweden intends to propose the following classifications:
• Skin Sens. 1, H317 - May cause an allergic skin reaction.
• Muta. 2, H341 - Suspected of causing genetic defect.
• Repr. 1B, H360FD - May damage fertility. May damage the unborn child.
• STOT RE 2, H373 - May cause damage to organs through prolonged or repeated exposure.
• Aquatic Acute 1, H400 - Very toxic to aquatic life.
• Aquatic Acute 1, M-factor=1000
• Aquatic Chronic 1, H410 - Very toxic to aquatic life with long lasting effects.
• Aquatic Chronic 1, M-factor=100
If the process is completed, Silver Chloride could be listed as a mutagenic and reprotoxic substance (and therefore CMR), and its use in cosmetic products …
