On 27 October 2026, the European Commission launched two consultations relating to the new hazard classes “Endocrine disruptor”, “PBT” and “vPvB” in the CLP Regulation. This has an immediate impact on 15 substances currently permitted for use in cosmetic products.
The first draft text under consultation aims to add to Annex VI of the European CLP Regulation No.1272/2008 on the classification, labelling and packaging of chemical substances those substances already identified as endocrine disruptors or persistent pollutants under the REACH, Biocidal Products and Plant Protection Products Regulations.
It concerns a total of 107 substances. Fifteen of these have an INCI name and do not appear in Annex II (prohibited substances) of the Cosmetics Regulation No.1223/2009 (or the prohibition set out in Annex II has not yet come into full effect).
The substances concerned
• octamethyltrisiloxane; [L3]
-> CAS No.107-51-7, EC No.203-497-4, INCI: Trisiloxane
-> Classified as vPvB, EUH441 - Strongly accumulates in the environment and living organisms including in humans
-> Not regulated in cosmetics
• dodecamethylcyclohexasiloxane; [D6]
-> CAS No.540-97-6, EC No.208-762-8, INCI: Cyclohexasiloxane
-> Classified as PBT, EUH440 - Accumulates in the environment and living organisms including in humans, and vPvB, EUH441 - Strongly accumulates in the environment and living organisms including in humans
-> Prohibited by Regulation (EU) 2024/1328 at a concentration of 0.1 per cent by weight or higher in rinse-off cosmetic products from 6 June 2026, and in leave-on cosmetic products from 6 …
